Azuki-chan is a manga series about a young schoolgirl named Azusa Noyama, nicknamed Azuki-chan because when she was younger she was accidentally called Azuki instead of Azusa. 
She always hated the name until one day a new boy starts in the same class as her called Y&#363;nosuke Ogasawara, the same day she is teased by a boy called Ken-chan about her nickname. Y&#363;nosuke-kun passes by and happily memorizes the name becoming the first girl he notices. Azuki is over joyed, and instantly falls in love with him, loving both him and her nickname. 
However Azuki gets jealous when she sees him chatting to other girls and cannot work out why he doesn't realize her love. 
(Source: Wikipedia)

Azusa Noyama is a 12-year-old girl student, taking 5th grade, but everyone knows her as Azuki-Chan, nickname that she dislikes. Yuunosuke Ogasawara, a new student, asks her about her nickname, saying that he likes it. Azuki falls in love with him, and they start going out together. They share a diary, and become boyfriend and girlfriend.
 
(Source: Anime News Network)

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