Ungrar, the King of Viruses, has escaped from his prison cell in Vaccine World. Maya, the Goddess of Vaccine World sends Mugimaru down to Earth to find a human to accept the powers of Vaccine World and become the Magical Nurse. He finds the best (and the only willing) person for the job when he meets Komugi Nakahara. Komugi is a playful, lazy, and easily distracted (typical) teenager whose dream is to become a cosplay idol. Balancing her career with the Kiri-Pro Promotion Company and her new job battling Ungrar's loyal henchman, the Magical Maid Koyori, Komugi delights audiences in this parody anime series. 
(Source: Anime News Network)

TV special, known as episode 2.5, takes place between episodes 2 and 3.
 
(Source: Anime News Network)

After the human colony on the moon was destroyed by disease, Kyosuke Date and his mother flee to Earth- separated from their family. They take refuge in a cathedral where his mother hides as a nun for reasons unknown to Kyosuke. After dangerous people find their sanctuary, his mother stabs him before she herself is murdered. 
Days later, Kyosuke finds himself alive and in the house of a mysterious girl who claims to be his twin Runa- and she is not the only one! Runa suffered a similar fate at the hands of her adoptive mother; however her soul was divided into several pieces making "flicker girls" who are being hunted by the evil Kirihara Group. The reason Kyosuke survived: his body's DNA conformed to the disease and he is able to transform into a fearsome alien mutant known as the SoulTaker. 
Kyosuke begins his battle against a hospital of evil mutants and dangerous corporate assassins in order to save himself and the sister he has never known.

Komugi Yoshida is a somewhat clumsy second-year middle-school student whose strong point is her spiritedness. She performs as an idol like Kokona Saionji (her classmate and close friend) and Tsukasa Kisaragi (an idol who dresses in male clothing). However, unlike Kokona whose popularity is skyrocketing and Tsukasa with her charisma in male attire, Komugi's only gigs are low-end ones like those at the local shopping district. Still, Komugi has her "dream" as she lives her dual lives as a idol and a middle school girl. 
 
One day, a mysterious injured creature named Usa-P appears before Komugi. Komugi gives Usa-P medical treatment, and Usa-P, in consideration of Komugi's kindness, asks if she wants to be a Legendary Girl who can use magical powers. 
 
Having become a reluctant Legendary Girl, Komugi battles strange masked figures who suddenly appear! As a newly deemed Magical Nurse, she fights still more waves of masked figures. Meanwhile, a Magical Maid, a Magical Sister, and more also appear to make it a three-way battle!? Can Komugi handle the three roles of middle school girl, idol, and Magical Nurse? And, what lies ahead in these battles and her "dream" …!?
 
(Source: Anime News Network)

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