This entry is for the 2007 movie, not to be confused by the first arc of the 2012 TV anime adaptation of Jojo's Bizarre Adventure, also named Phantom Blood. Nor the movie format 're-edit' of said first season compiled from the 2012 TV episodes. 
Jonathan Joestar is an aristocratic boy whose life is suddenly turned upside down by a mysterious new boy who arrives, Dio Brando. Dio has a connection to his father, and over time, a rivalry forms as Dio becomes obsessed with a mysterious, ancient, and mystical stone mask that Jonathan's father keeps. 
Note: This film hasn't been released publicly outside of its original limited theatrical run and is considered mostly lost, apart from several trailers and a found 16-minute undubbed clip compilation used for a student sound design assignment. (Source: Lost Media Wiki)

Young Jonathan Joestar’s life is forever changed when he meets his new adopted brother, Dio. For some reason, Dio has a smoldering grudge against him and derives pleasure from seeing him suffer. But every man has his limits, as Dio finds out. This is the beginning of a long and hateful relationship!
 
(Source: Viz Media)

Beginning its tale in 19th century England, young aristocrat Jonathan Joestar finds himself locked in bitter rivalry with Dio Brando, a low-born boy who Jonathan's father took under his wing after the death of Dio's father. Discontent with his station in life, Dio's fathomless lust to reign over all eventually leads him to seek the supernatural powers of an ancient Aztec stone mask in the Joestar's possession—an artifact that will forever change the destiny of Dio and Jonathan for generations to come. 
 
Fifty years later, in 1938 New York City, Jonathan's grandson Joseph Joestar must take up his grandfather's mission and master the abilities necessary to destroy the stone mask and its immensely powerful creators who threaten humanity's very existence, the Pillar Men. 
(Source: Anime News Network)

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