Appleseed Alpha depicts the early days of Deunan Knute and Briareos in the 22nd century, as they embark on a journey throughout dystopic ruins of New York in search of the city of Olympus. They are hired by Two Horns, the warlord of the ruined city, to eliminate bipedal combat machines. During the fight, they encouter Iris and Olson, both on a mission. Deunan and Briareos befriend with them and decide to join their mission. 
 
Iris is tasked with preventing the malevolent cyborg Talos from capturing a secret weapon humans were building. Talos uses Iris to activate the gigantic war machine. 
 
(Source: Wikipedia)

Growing out of the chaos of a global war, the city of Utopia is populated by humans and bioroids (artificial humans). On the surface, everything is harmonious, but tensions lurk. Into this seemingly perfect society comes a survivor of the wars, Deunan Knute, who carries a legacy that will turn out to be of critical importance to the future of humanity. 
(Source: Anime News Network)

Before the events of Appleseed, Deunan, a human woman and former SWAT officer, along with her combat-cyborg lover, Briareos, arrive in war-torn New York City. The city’s mayor is a dapper but delusional cyborg, preparing for the UFO invasion he’s convinced is right around the corner. Briareos’s powerful abilities earn the pair refuge, but there are few human comforts to be found in a city catered to cyborgs …
 
After the couple parts ways, the mayor’s nightmare takes a turn for the worse. Deunan’s group of outcast humans may be just the extra manpower the mayor needs—but can the two factions put aside their differences in time to save the world?
 
(Source: Kodansha USA)

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