In Osomatsu-san: Hipipo-zoku to Kagayaku Kajitsu, the sextuplets embark on a grand adventure in search of a legendary fruit that is said to grant the greatest wish of whomever consumes it. 
(Source: Crunchyroll, edited) 

Note: To commemorate the 6th anniversary of Osomatsu-san anime, two new animation projects that will have a theatrical release were announced at the "Fes Matsu-san '21" event, with one in 2022, and the other the following year.

The Matsuno sextuplets (leader Osomatsu, wannabe tough guy Karamatsu, straight man Choromatsu, cynical Ichimatsu, cheerfully stupid Jyushimatsu and lovable spoiled Todomatsu) are now in their 20s, still living together in the same house as NEETs. Their neighbors still include such eccentric characters as fish market idol Totoko, loud bucktoothed troublemaker Iyami, tiny rival Chiba, wacky inventor Dekapan, and giant mouthed glutton Dayon. 
 
Join the Matsuno siblings as they overcome mundane hurdles in their daily lives, such as finding employment, figure out who should pay the bar bill, and who should get the extra pastry!

The third season of Osomatsu-san.

In Osomatsu-san: Tamashii no Takoyaki Party to Densetsu no Otomari-kai, the story begins with the sextuplets prepping for a takoyaki-cooking party at their home, before everything goes haywire when Totoko implies a sleepover. 

(Source: Anime News Network, edited)
 

Note: To commemorate the 6th anniversary of Osomatsu-san anime, two new animation projects that will have a theatrical release were announced at the "Fes Matsu-san '21" event, with one in 2022, and the other the following year.

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